MT-1
Melanotan I, a linear alpha-MSH analogue (afamelanotide), used in pigmentation research.
- 1–2 pcs€40 each
- 3+ pcs€36 each−10%
- 10+ pcs€32 each−20%
- Certificate of analysis for every batch
- Over 99% verified purity
- Ships from Norway
- Free shipping over NOK 2,500
Description and specifications
Description
MT-1 (Melanotan I, also known as afamelanotide) is a synthetic linear tridecapeptide analogue of alpha-melanocyte-stimulating hormone (alpha-MSH). In research models, the peptide is investigated for its role in melanogenesis via the melanocortin-1 receptor and as a photoprotective mechanism in skin cells. Supplied as a lyophilised powder for laboratory use. For research use only (in vitro / laboratory use). Not for consumption, diagnostic or therapeutic use.
Research summary
MT-1 (Melanotan I) is a synthetic variant of the body's own signalling substance alpha-MSH. It binds to a receptor called MC1R on the pigment cells in the skin, and has been studied because it can increase the skin's production of the dark pigment eumelanin. A purified medicinal version, afamelanotide (brand name SCENESSE), is approved in the EU, the USA and Australia for a rare inherited light-sensitivity disorder. All content here is for research purposes only.
Level of evidence: The purified medicinal version afamelanotide (SCENESSE) has randomised human studies and is approved for EPP. For the other areas (vitiligo, solar urticaria, general pigmentation) the evidence base is more limited and often consists of small or single studies. Generic "melanotan" sold outside pharmaceutical channels is not the same as the controlled medicine and is not quality-assured. None of this is medical advice.
This information is written for a laboratory and research context. The product is not intended for consumption, diagnostics or therapeutic use.
Specifications
| CAS | 75921-69-6 |
| Molecular formula | C78H111N21O19 |
| Purity | ≥ 99 % (HPLC) |
| Size | 10 mg |
Batch information
Batch number, purity and document status are shown here for each published batch.
Need the certificate of analysis?
Contact ArcticAmino to receive a copy of the certificate of analysis (COA) for the product or batch.
Peptide guide
Research Use Only. Not for human consumption. Not medical advice. Always check information against primary sources and internal laboratory procedures.
Read the full guide (10 studies)MT-1, Melanotan I (afamelanotide)
MT-1 mimics alpha-MSH and activates the MC1R receptor on melanocytes (pigment cells). When this receptor is activated, the cells shift production towards more eumelanin, the dark type of pigment that absorbs UV light and captures free radicals. In skin studies this has been measured as increased pigment density and less UV-induced DNA damage. Unlike ordinary tanning, which only starts pigmentation after UV damage has occurred, MT-1 acts independently of sun exposure.
What is being researched?
- Erythropoietic protoporphyria (EPP), a rare inherited light-sensitivity disorder, in which the medicinal version afamelanotide has been investigated in randomised human studies
- Skin pigmentation and photoprotection: increased eumelanin and reduced UV/DNA damage in the skin of healthy volunteers
- Vitiligo: repigmentation of white skin patches, explored together with narrowband UVB light therapy
- Other light-sensitivity conditions, such as solar urticaria (sun allergy), investigated in smaller studies
Selected sources
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Why researchers choose ArcticAmino
- Certificate of analysis for every batch
- Over 99% verified purity
- Ships from Norway
- Next-day delivery
- Discreet packaging
- Norwegian customer service
- Free shipping over NOK 2,500
- For research purposes only
