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Retatrutide
Synthetic triple agonist of the GIP, GLP-1 and glucagon receptors, used in metabolic research.
- 1–2 pcs€75 each
- 3+ pcs€68 each−10%
- 10+ pcs€60 each−20%
- Certificate of analysis for every batch
- Over 99% verified purity
- Ships within 24 hours
- Free shipping over €250
Description and specifications
Description
Retatrutide (LY3437943) is a synthetic 39-amino-acid peptide analogue that acts as an agonist at three receptors simultaneously: GIP, GLP-1 and glucagon. In research models, the molecule is studied for its role in appetite regulation, glucose metabolism and energy expenditure. Supplied as a lyophilised powder for reconstitution in the laboratory. For research use only (in vitro / laboratory use). Not for consumption, diagnostic or therapeutic use.
Research summary
Retatrutide (development name LY3437943) is a synthetic peptide that mimics three of the body's own hormone signals at the same time – GIP, GLP-1 and glucagon. The peptide is being investigated in large clinical studies in humans in the fields of metabolism and weight. This page summarises the research for informational purposes; it is not medical advice, and the product is intended for research use only.
Level of evidence: Several randomised phase 2 studies in humans (published in journals including the New England Journal of Medicine and The Lancet) show a large effect on weight and blood sugar, and phase 3 studies are now under way or recently published. At the same time, the substance is still being tested and has not completed approval as a medicine; long-term effects and safety have not yet been fully mapped, and the studies are largely funded by the manufacturer. The content here is research information, not health advice.
This information is written for a laboratory and research context. The product is not intended for consumption, diagnostics or therapeutic use.
Specifications
| CAS | 2381089-83-2 |
| Molecular formula | C221H342N46O68 |
| Purity | ≥ 99 % (HPLC) |
| Size | 5 mg / 20 mg |
Batch information
Batch number, purity and document status are shown here for each published batch.
Need the certificate of analysis?
Contact ArcticAmino to receive a copy of the certificate of analysis (COA) for the product or batch.
Peptide guide
Research Use Only. Not for human consumption. Not medical advice. Always check information against primary sources and internal laboratory procedures.
Read the full guide (11 studies)Retatrutide (LY3437943)
Most newer molecules in this class target one or two hormone systems. Retatrutide targets three at once. GLP-1 and GIP are gut hormones that affect insulin, appetite and how quickly the stomach empties. The glucagon signal has been added because it can increase the body's energy expenditure and affect how the liver and fat tissue process energy. Researchers are exploring whether this three-part action produces a stronger effect on weight and metabolism than earlier molecules.
What is being researched?
- Body weight and obesity (phase 2 studies with marked weight loss)
- Blood sugar control in type 2 diabetes
- Fat in the liver and fatty liver disease (MASLD)
- Body composition – fat and muscle mass
- Ongoing phase 3 studies in obesity, sleep apnoea and knee osteoarthritis
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Why researchers choose ArcticAmino
- Certificate of analysis for every batch
- Over 99% verified purity
- Ships within 24 hours
- Ships within 24 hours
- Discreet packaging
- Customer service by email and Telegram
- Free shipping over €250
- For research purposes only
Often ordered together for lab set-ups.
